Adrenal Lesions in the Baboon (Papio spp)-Reference-Cited by-同舟云学术

Adrenal Lesions in the Baboon (Papio spp)

Published:1985-03 Issue:2 Volume:22 Page:141-146
ISSN:0300-9858
Container-title:Veterinary Pathology
language:en
Short-container-title:Vet Pathol

Author:

Skelton-Stroud P. N.¹,Ishmael J.¹

Affiliation:

1. Ciba-Geigy Pharmaceuticals, Stamford Lodge, Altrincham Road, Wilmslow, Cheshire, UK and Imperial Chemical Industries PLC, Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, UK

Abstract

A histological survey was conducted on 604 pairs of adrenal glands from yellow ( Papio cynocephalus) and olive ( Papio anubis) baboons used in drug safety evaluation studies. Spontaneous lesions were found in 372 glands—34 of which had more than one change. Cortical lesions consisted of accessory nodules (190), nodular hyperplasia (7), hepatoadrenal adhesion (18) and partial fusion (1), focal mineralization (20), ectopic bone marrow (6), and focal fatty change (60). Medullary lesions were confined to focal lymphocytic (66) and plasma cell (1) infiltrates.

Publisher

SAGE Publications

Subject

General Veterinary

Link

http://journals.sagepub.com/doi/pdf/10.1177/030098588502200208

Reference23 articles.

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5. Combined Adrenorenal Fusion and Adrenohepatic Adhesion: A Case Report with Review of the Literature and Discussion of Pathogenesis

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