Author:
Noda Y.,Uchinuno Y.,Shirakawa H.,Nagasue S.,Nagano N.,Ohe R.,Narita M.
Abstract
A bovine fetus aborted at 187 days of gestation was serologically and immunohistopathologically examined. Serum and cerebrospinal fluid samples had high titers of virus-neutralizing antibody for Aino virus. A severe necrotizing encephalopathy was noted. Aino virus antigen was demonstrated in neuroglial cells within the brain lesion. The destruction of developing neuronal cells appeared to be a significant feature of the pathogenesis of lesions due to Aino virus infection in the central nervous system.
Cited by
19 articles.
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