Affiliation:
1. Aus dem Institut für Veterinär-Pathologie der Humboldt-Universität Berlin (damaliger Direktor: Prof. Dr. D. Matthias) und dem Institut für Vergleichende Pathologie der Deutschen Akademie der Wissenschaften zu Berlin (Direktor: Prof. Dr. D. Matthias)
Abstract
Early changes in photodynamic dermatitis of a 12-year-old black-spotted cow (Holstein cross) were characterized by splitting of collagen fibers and loss of acid mucopolysaccharides which were believed to be the result of a process of disaggregation and depolymerization. The resorcin- and fuchsinophilic material in the chronically inflammed corium was shown histochemically to be a mucoprotein similar to the cement substance in pathologically altered elastic fibers. Necrosis of connective tissue and a defective but increased synthesis of fibers were considered responsible for the production of this material. Finally, the comparative pathological aspects of this “elastotic” degeneration of connective tissue were discussed.