Cytoplasmic Inclusions in Urinary Bladder Epithelium of the Rhesus Monkey A Histochemical, Light- and Electron-Microscopic Study

Abstract

Cytoplasmic inclusions in urinary bladder epithelium found in nine of 155 Rhesus monkeys were examined. The inclusions were brightly eosinophilic in HE-stained sections. In the electron microscope the inclusions appeared as bundles of filaments. They were not associated with viral particles, were not membrane-bound, and appeared to have a continuity with normal tonofilaments. They apparently contain protein, but neither DNA nor RNA were demonstrated by various histochemical methods.