Sheep With the Homozygous Lysine-171 Prion Protein Genotype Are Resistant to Classical Scrapie After Experimental Oronasal Inoculation
Author:
Affiliation:
1. Department of Veterinary Pathology, Iowa State University, Ames, IA, USA
2. United States Department of Agriculture, Virus and Prion Research Unit, National Animal Disease Center, Agricultural Research Service, Ames, IA, USA
Abstract
Publisher
SAGE Publications
Subject
General Veterinary
Link
http://journals.sagepub.com/doi/pdf/10.1177/0300985818817066
Reference34 articles.
1. A case of scrapie in a sheep carrying the lysine-171 allele of the prion protein gene
2. Low frequency of the scrapie resistance-associated allele and presence of lysine-171 allele of the prion protein gene in Italian Biellese ovine breed
3. APHIS: Scrapie Free Flock Certification Program: Scrapie Program Standards. 2016. USDA, APHIS, Veterinary Services. Riverdale, MD.
4. Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie
5. PrP genotype contributes to determining survival times of sheep with natural scrapie
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4. A Mass Spectrometry-Based Method of Quantifying the Contribution of the Lysine Polymorphism at Position 171 in Sheep PrP;Journal of the American Society for Mass Spectrometry;2023-01-09
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