Chemical gastro-oesophagitis, upper gastrointestinal haemorrhage and gastroscopic findings following Dettol poisoning

Author:

Chan Thomas Y.K.1,Sung Joseph J.Y.2,Critchley Julian A.J.H.1

Affiliation:

1. Departments of Clinical Pharmacology, The Chinese University of Hong Kong

2. Department of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong

Abstract

1 Dettol liquid (chloroxylenol 4.8%, pine oil, isopropyl alcohol), a household disinfectant, has a corrosive action on the gastrointestinal mucosa when swallowed. The inci dence of upper gastrointestinal haemorrhage and gastro scopic findings following Dettol poisoning was studied in 89 patients. 2 Five patients (5.6%) developed minor haematemesis, in the form of coffee-coloured or blood-stained vomitus. One patient had a gastroscopy performed on the day after admission, showing signs of chemical burns in the oesoph agus and stomach. Gastroscopy was performed in one other patient on day 11 to rule out oesophageal stricture; the patient was normal. All patients completely recovered. 3 The data from this study suggest that upper gastroin testinal haemorrhage following Dettol poisoning tends to be mild and self-limiting. Gastroscopy, which may increase the risk of aspiration in patients with impaired consciousness, is not required unless other causes of gas trointestinal bleeding are suspected.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Multiorgan failure and death from a mixed Dettol and Clorox poisoning: a case report;Journal of Medical Case Reports;2023-03-16

2. Factors that affect mortality in local patients who ingested common household cleansing products and required intubation;Hong Kong Journal of Emergency Medicine;2019-09-20

3. Clinical pathomorphology and tanatogenesis of various forms of alcoholic intoxication;Sudebno-meditsinskaya ekspertiza;2018

4. Chloroxylenol;Meyler's Side Effects of Drugs;2016

5. DISINFECTANTS AND ANTISEPTICS;Meyler's Side Effects of Antimicrobial Drugs;2010

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