Charcoal and Isoniazid Pharmacokinetics-Reference-Cited by-同舟云学术

Charcoal and Isoniazid Pharmacokinetics

Published:1986-07 Issue:4 Volume:5 Page:285-286
ISSN:0144-5952
Container-title:Human Toxicology
language:en
Short-container-title:Human Toxicology

Author:

Scolding N.¹,Ward M.J.¹,Hutchings A.¹,Routledge P.A.¹

Affiliation:

1. Department of Clinical Pharmacology, University of Wales College of Medicine, Llandough Hospital, South Glamorgan CF6 1XX, Wales, UK

Abstract

Activated charcoal (10 g) administered 1 h after a 600 mg oral dose of isoniazid to six healthy subjects did not reduce the area under the plasma concentration-time curve for isoniazid significantly. Charcoal administration is unlikely to be of value in isoniazid poisoning if delayed by an hour or more after the overdose.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://journals.sagepub.com/doi/pdf/10.1177/096032718600500414

Reference4 articles.

1. Optimal antidotal dose of activated charcoal

2. A method to prevent the loss of isoniazid and acetylisoniazid in human plasma.

3. High-performance Liquid chromatographic analysis of isoniazid and acetylisoniazid in biological fluids

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