Affiliation:
1. Institute of Toxicology, National Food Agency, 19, Mørkhøj Bygade, DK-2860 Søborg, Denmark
Abstract
1 The existing prevalence estimates of food additive intolerance1-4 are being reviewed. 2 In the EEC report the estimated frequency of food additive intolerance is 0.03% to 0.15% based on data from patient groups. 3 The British population study results in a prevalence estimate of 0.026%. The challenged population is 81 children and adults with a history of reproducible clinical symptoms after ingestion of food additives. 4 In the Danish population study a prevalence of 1-2% is found in children age 5-16. In this study a total of 606 children mainly with atopic disease have been challenged. 5 The prevalence estimates vary with a factor 100. As the results vary so do the study populations. 6 If the different study populations are accounted for, a common conclusion can be drawn: Food additive intolerance is found in adults with atopic symptoms from the respiratory tract and skin. The prevalence estimates are questionable but may be less than 0.15%. In adults and children with reproducible, and with more subjective symptoms, such as headache and behavioural/mood change the prevalence is even lower (0.026%). Food additive intolerance is primarily found in atopic children with cutaneous symptoms where the additive is aggravating an existing disease. The prevalence of food additive intolerance in children age 5-16 is 1-2%.
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Reference19 articles.
1. Commission of the European Communities. Report of a working group on adverse reactions to ingested additives. Reports of the Scientific Committee for Food. Twelfth series: EUR 7823, 1982, pp. 6-26.
2. Prevalence of intolerance to food additives among Danish school children
Cited by
15 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献