An Immunological Study on Workers Occupationally Exposed to Cadmium

Author:

Karakaya A.1,Yücesoy B.1,Sardas O.S.2

Affiliation:

1. Department of Toxicology, Faculty of Pharmacy Ankara University, 06100, Tandogan, Ankara, Turkey

2. Department of Haematology, Faculty of Medicine, Ankara University, 06100, Tandogan, Ankara, Turkey

Abstract

1 To assess the quantitative relation between exposure to airborne cadmium and various markers of immune function, 37 male workers were examined and compared with unexposed controls. 2 Blood cadmium concentrations were signficantly , higher in the exposed workers than in the unexposed, as was urine cadmium. 3 No differences in the serum immunoglobulin (IgG, IgM and IgA) levels between two popularions were observed, There was also no significant correlation between blood cadmium concentrations and serum immunoglobulin levels of both exposed and control groups, It has been found also that while monocyte counts signficantly increased, lymphocyte, neutrophil and oesinophil counts remained unchanged.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference12 articles.

1. Descotes J. Immunotoxicology of Drugs and Chemicals, pp. 299-304. Amsterdam, Elsevier, 1988.

2. In vitro evaluation of cadmium-induced augmentation of the antibody response

3. Koller LD Immunosuppression produced by lead, cadmium and mercury. American Journal of Veterinary Research 1973; 34: 1457-8.

4. Evaluation of host resistance and immune function in cadmium-exposed mice

5. Effects of cadmium and zinc on spontaneous and antibody‐dependent cell‐mediated cytotoxicity

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