Affiliation:
1. Guy's Hospital, St. Thomas Street, London SE1 9RT, UK
Abstract
A 48-year-old woman developed QT prolongation and episodes of life-threatening ventricular tachycardia (torsades de pointes) after intentional overdose of haloperidol and orphenadrine. The arrhythmia did not respond to conventional anti-arrhythmic therapy but was suppressed by atrial overdrive pacing. A literature review identified haloperidol as the most likely cause of the torsades de pointes.
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Cited by
54 articles.
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