Nomifensine and Convulsive Seizures-Reference-Cited by-同舟云学术

Nomifensine and Convulsive Seizures

Published:1987-05 Issue:3 Volume:6 Page:247-249
ISSN:0144-5952
Container-title:Human Toxicology
language:en
Short-container-title:Human Toxicology

Author:

Guy Edwards J.¹,Glen-Bott M.²

Affiliation:

1. Department of Psychiatry, Royal South Hampshire Hospital, Southampton, SO9 4PE

2. Medicines Division, Department of Health and Social Security, Market Towers, London, SW8 5NQ, UK

Abstract

Four cases of convulsive seizures occurring during treatment with nomifensine have been notified to the Committee on the Safety of Medicines of the United Kingdom, and 22 cases have been reported from other countries. The occurrence of convulsions is not in keeping with the results of animal experiments, studies of epileptic patients treated with nomifensine or observations made following overdoses of this drug. Nomifensine may thus not be entirely free from epileptogenic properties as previously presumed.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://journals.sagepub.com/doi/pdf/10.1177/096032718700600314

Reference23 articles.

1. ANTIDEPRESSANTS AND CONVULSIONS

2. Edwards JG Antidepressants and convulsive seizures: epidemiological and clinical aspects . In The Psychopharmacology of Epilepsy, ed MR Trimble, pp. 119-139. Chichester: John Wiley, 1985.

3. Effect of nomifensine on brain amines and epilepsy in photosensitive baboons.

4. Seizures with Antidepressants: An In Vitro Technique to Assess Relative Risk

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