Neutrophil Functions in Lead-Exposed Workers-Reference-Cited by-同舟云学术

Neutrophil Functions in Lead-Exposed Workers

Published:1990-07 Issue:4 Volume:9 Page:231-233
ISSN:0960-3271
Container-title:Human & Experimental Toxicology
language:en
Short-container-title:Hum Exp Toxicol

Author:

Bergeret A.¹,pouget E.¹,Tedone R.²,Meygret T.¹,Cadot R.¹,Descotes J.²

Affiliation:

1. Institut Universitaire de Medecine du Travail, 8 Avenue Rockefeller

2. Laboratoire d'Immunotoxicologie Fondamentale et Clinique, INSERM U80-CNRS URA1177-UCBL, FacuIté de Médecine Alexis Carrel, 69008 Lyon, France

Abstract

Neutrophil functions were studied in 38 lead-exposed workers compared to 34 controls. Both groups were matched according to age, sex, drinking and smoking habits, ethnic origin and drug intake. Blood lead levels were found to be seven times higher in exposed workers than in controls. Phagocytosis assayed by chemiluminescence was found to be slightly but not significantly altered in exposed workers. In contrast, chemotaxis using the agarose technique was significantly depressed. These results are in agreement with previous in-vitro findings. A further assessment of clinical consequences is warranted.

Publisher

SAGE Publications

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/096032719000900405

Reference12 articles.

1. Serum immunoglobulin, complement C3, and salivary IgA levels in lead workers

2. Evaluation of the humoral immune response of children with low level lead exposure

3. Influence of chronic low-level exposure to lead on plasma immunoglobulin concentration and cellular immune function in man

4. In vitro impairment of human granulocyte functions by lead

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