On-line mass spectrometry: a review

Abstract

The technique of on-line mass spectrometry is placed in its historical context indicating how increased reliability of vacuum systems and electronic developments have led to its reinstatement as a viable on-line analytical tool. The basic principles of mass spectrometry are discussed, indicating how the instruments may be classified with reference to their source, analyser and detector components. The advantages of using mass spectrometry for process analysis are discussed. A survey of the literature concerning on-line mass spectrometry is given, indicating its range of applications. The current limitations of the various types of commercial instrument available are discussed, and some opinions are expressed as to the likely future development of the instrumentation. Computer control and data processing are particularly relevant in this technique, and a review of current philosophies is undertaken together with an indication of their implications in the cost and efficiency of a total instrument package. A view is expressed of the current status of the technique as a practical process instrument indicating maintenance calibration and technical supervision requirements.