Correlates of total perfusion time, clamp time and nonclamp perfusion time in coronary bypass surgery

Abstract

Longer perfusion and clamp times are associated with greater mortality and morbidity. We studied the factors which correlate with the duration of perfusion time, clamp time and nonclamp perfusion time in 1078 patients having coronary bypass surgery. Perfusion time correlated significantly ( P≤ 0.05) with female sex, ejection fraction, left ventricular diastolic pressure, number of distal anastomoses, incomplete revascularization, atherosclerotic aorta, aorto-iliac-femoral occlusive disease and date of operation. Only the number of distal anastomoses, incomplete revascularization, atherosclerotic aorta, ejection fraction and date of operation correlated significantly ( P≤ 0.05) with perfusion time with multiple regression analysis. Factors significantly ( P≤ 0.05) correlating with nonclamp perfusion time included age, ejection fraction, left ventricular end diastolic pressure, number of distal anastomoses, incomplete revascularization, atherosclerotic aorta and aorto-iliac-femoral occlusive disease. Multiple regression analysis showed that only ejection fraction, number of distal anastomoses, incomplete revascularization and atherosclerotic aorta significantly ( P≤ 0.05) contributed to the predication of nonclamp perfusion time. The individual correlates ( P≤ 0.05) of clamp time included age (negative correlation), female sex, ejection fraction, height, weight, body surface area, number of distal anastomoses, incomplete revascularization, atherosclerotic aorta and date of operation. Multiple regression analysis shows that clamp time correlates significantly ( P ≤ 0.05) with the number of distal anastomoses, date of operation, age, incomplete revascularization, atherosclerotic aorta and female sex.