Pilot validation of an individualised pharmacokinetic algorithm for protamine dosing after systemic heparinisation for cardiopulmonary bypass
Author:
Affiliation:
1. Department of Anaesthesia, Austin Health, Heidelberg, Victoria, Australia
2. Cambridge Perfusion LLC, Cambridge, UK
3. Department of Anaesthesia and Intensive Care, Papworth Hospital NHS Foundation Trust, UK
Abstract
Publisher
SAGE Publications
Subject
Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Safety Research,Radiology, Nuclear Medicine and imaging,General Medicine
Link
http://journals.sagepub.com/doi/pdf/10.1177/0267659117695881
Reference40 articles.
1. Les différentes alternatives d’anticoagulation au couple héparine/protamine en chirurgie cardiaque sous circulation extra-corporelle
2. Adverse reactions to protamine sulfate following cardiac surgery
3. The effects of protamine overdose on coagulation parameters as measured by the thrombelastograph
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1. Optimal protamine dosing after cardiopulmonary bypass: The PRODOSE adaptive randomised controlled trial;PLOS Medicine;2021-06-07
2. Are We Able to Dose Protamine Accurately Yet? A Review of the Protamine Conundrum;The Journal of ExtraCorporeal Technology;2020-03
3. Analysis of the Action of Quaternized Chitosans with Different Molecular Weight on Anticoagulant Activity of Heparins In Vitro;Bulletin of Experimental Biology and Medicine;2019-06
4. Calculation Algorithm Reduces Protamine Doses Without Increasing Blood Loss or the Transfusion Rate in Cardiac Surgery: Results of a Randomized Controlled Trial;Journal of Cardiothoracic and Vascular Anesthesia;2019-04
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