“Drum Tower Hospital” strategy for acute type A aortic dissection with coma

Author:

Wang Ya-peng1ORCID,Lu Li-chong2345,Li Shu-chun2345,Li Li2345,Jiang Yi1,Cheng Yong-qing2345,Ge Min2345,Chen Yang2345,Wang Dong-jin12345

Affiliation:

1. Department of Cardio-Thoracic Surgery, Nanjing Drum Tower Hospital, Peking Union Medical College Graduate School, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, China

2. Department of Cardiothoracic Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing Drum Tower Hospital, Nanjing, China

3. Institute of Cardiothoracic Vascular Disease, Nanjing University, Nanjing, China

4. Department of Cardio- Thoracic Surgery, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing, Jiangsu, China

5. Nanjing Drum Tower Hospital, Xuzhou Medical University, Xuzhou, Jiangsu, China

Abstract

Overview Acute type A aortic dissection (ATAAD) with persistent coma is a life-threatening condition associated with high mortality and poor neurological outcomes. The optimal timing for surgical intervention in these patients remains uncertain, and many patients are not eligible for surgery due to their poor prognosis. Description In this case, a 53-year-old man with hypertension presented to the emergency department in a coma that had lasted for 9 hours. The patient was diagnosed with ATAAD and underwent the “Drum Tower Hospital” strategy, which involved preoperative assessments, including computed tomography angiography (CTA) and quantitative electroencephalogram (qEEG) monitoring. Surgical interventions, such as emergency stenting and aortic replacement, were performed to restore blood flow and repair the aorta. Postoperative monitoring, including qEEG, showed improvements in brain function. Despite the patient experiencing hemiplegia and a neurological deficit, the “Drum Tower Hospital” strategy, guided by comprehensive brain assessments, showed promise in managing ATAAD with coma. However, further research is needed to establish effective treatment strategies for these patients. Overall, ATAAD with persistent coma is a critical condition with limited treatment options. The “Drum Tower Hospital” strategy, supported by multimodal brain assessment, offers a potential approach to improve outcomes in these patients.

Funder

Jiangsu Province Capability Improvement Project through Science, Technology and Education

Publisher

SAGE Publications

Subject

Advanced and Specialized Nursing,Cardiology and Cardiovascular Medicine,Safety Research,Radiology, Nuclear Medicine and imaging,General Medicine

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