Decrease of Total Serum Cholesterol and Apolipoproteins A1 and B Levels during and after Extracorporeal Circulation
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Published:1987-04
Issue:2
Volume:2
Page:97-100
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ISSN:0267-6591
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Container-title:Perfusion
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language:en
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Short-container-title:Perfusion
Author:
Seguin Jacques R1,
de Paulet Pierrette Crastes1,
de Paulet Jacques Crastes1,
Chaptal Paul A1
Affiliation:
1. CHU Hopital Saint-Eloi and CHU Hopital Lapeyronie. Montpellier
Abstract
Cholesterol, apolipoproteins A1 and B and triglycerides were evaluated before, during and after extracorporeal circulation during cardiac surgery to a precise degree and chronology of variations. Cholesterol, apolipoprotein B and triglycerides show a significant and persistent decrease following initiation of extracorporeal circulation. Triglycerides decrease is due to factors such as heparin administration. Cholesterol and apolipoprotein B decrease does not appear to be due either to contact with extracorporeal circulation circuit nor hypothermia. Decrease of hepatic VLDL and HDL production or modifications of LDL-cholesterol cell clearance are possible explanations.
Publisher
SAGE Publications
Subject
Advanced and Specialised Nursing,Cardiology and Cardiovascular Medicine,Safety Research,Radiology Nuclear Medicine and imaging,General Medicine