Reliability of functional outcome measures in adults with neurofibromatosis 2

Author:

Mullin Rebecca Louise12ORCID,Smith Rebecca12,Wood Susan1,Swampillai Angela1,Afridi Shazia1

Affiliation:

1. National Centre for Neurofibromatosis, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

2. Department of Physiotherapy, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

Abstract

Objective: To determine inter- and intra-rater reliability of functional performance outcome measures in people with neurofibromatosis 2. To ascertain how closely objective and subjective measures align. Methods: Twenty-nine people with neurofibromatosis 2 were recorded performing the modified clinical test of sensory integration and balance, four square step test and modified nine-hole peg tests. Three raters scored each measure to determine inter-rater reliability. One rater scored the measures a second time to determine intra-rater reliability. Participants also completed a disease-specific quality of life questionnaire and dynamic visual acuity testing. Results: Inter-rater and intra-rater reliability scores (intra-class correlation coefficient) were excellent for all tests (intra-class correlation coefficient r ⩾ 0.9). The four square step test correlated with perceived walking challenges and modified clinical test of sensory integration and balance correlated with perceived balance challenges in a neurofibromatosis 2 quality of life patient report outcome measure. Conclusion: The modified clinical test of sensory integration and balance, four square step test and modified nine-hole peg tests are potentially useful measures for monitoring neurofibromatosis 2.

Funder

No additional funding was sought for this research

Publisher

SAGE Publications

Subject

General Medicine

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