Pharmacogenomics in IVF: A New Era in the Concept of Personalized Medicine-Reference-Cited by-同舟云学术

Pharmacogenomics in IVF: A New Era in the Concept of Personalized Medicine

Published:2018-03-27 Issue:10 Volume:26 Page:1313-1325
ISSN:1933-7191
Container-title:Reproductive Sciences
language:en
Short-container-title:Reprod Sci

Author:

Kalinderi Kallirhoe¹²,Asimakopoulos Byron³,Nikolettos Nikos⁴,Manolopoulos Vangelis G.⁵

Affiliation:

1. Department of General Biology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

2. 3rd Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Thessaloniki, Greece

3. Laboratory of Physiology, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece

4. Laboratory of Reproductive Physiology—In Vitro Fertilization, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece

5. Laboratory of Pharmacology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece

Abstract

Pharmacogenomics is a promising approach in the field of individualized medicine in in vitro fertilization (IVF) treatment that aims to develop optimized pharmacotherapy depending on the genetic background of each infertile woman, thus to ensure maximum effectiveness of the medication used, with minimal side effects. The unique genetic information of each infertile woman, in combination with already known, as well as new predictors of ovarian response and the progress of pharmacoepigenomics, is anticipated to greatly benefit the process of controlled ovarian stimulation. This review analyses current data on IVF pharmacogenomics, a new approach that is gradually moving to the frontline of modern IVF treatment.

Publisher

Springer Science and Business Media LLC

Subject

Obstetrics and Gynaecology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1933719118765970

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