The PADQOL: Development and validation of a PAD-specific quality of life questionnaire

Author:

Treat-Jacobson Diane1,Lindquist Ruth A1,Witt Dawn R1,Kirk Laura N1,Schorr Erica N1,Bronas Ulf G1,Davey Cynthia S2,Regensteiner Judith G34

Affiliation:

1. University of Minnesota School of Nursing, Minneapolis, MN, USA

2. University of Minnesota Clinical and Translational Institute, Minneapolis, MN, USA

3. University of Colorado School of Medicine, Aurora, CO, USA

4. Center for Women’s Health Research, University of Colorado School of Medicine, Aurora, CO, USA

Abstract

Understanding the impact of peripheral artery disease (PAD) requires broad evaluation of how functional limitations of PAD affect patients’ perceptions of health-related quality of life (HRQL). The objective of this study was to describe the development, testing, and psychometric properties of the PAD Quality of Life Questionnaire (PADQOL). The PADQOL was developed in three steps: (1) interviews of symptomatic PAD patients provided content of the initial questionnaire; (2) co-administration with the SF-36 (a 36-item short-form health survey), Walking Impairment Questionnaire, and Profile of Mood States examined construct validity; and (3) a three-phased factor analysis identified factors and shortened the questionnaire. Data analyses from 297 symptomatic PAD patients resulted in a 38-item questionnaire of five factors: Social relationships and interactions, Self-concept and feelings, Symptoms and limitations in physical functioning, Fear and uncertainty, and Positive adaptation (α = 0.92–0.73) and items related to sexual function, intimate relationships and employment. Between-instrument correlations established construct validity. In conclusion, PADQOL is a validated measure to assess the disease-specific physical, psychosocial and emotional effects of PAD for research and practice.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

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