A Rare Case of Deceptive Maxillary Ameloblastoma

Author:

Wu Yingjie1,Tian Yuan2,Niu Xun1,Yue Jianxin1,Cheng Qing1,Sun Haiying1,Zhou Liuqing1ORCID,Zhou Tao1

Affiliation:

1. Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

2. Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Abstract

Ameloblastoma (AM) is a rare epithelium-derived odontogenic tumor, mostly involving the mandible and less often the maxilla. Most AMs are benign and characterized by indolence and local invasiveness, with a high recurrence rate. Herein, we present a case of maxillary AM in a 42-year-old female suffering from left nasal congestion and facial swelling for almost one month after endoscopic surgery at a local hospital. The mass was completely resected by a transnasal functional endoscopic sinus surgery based on radiographic examination. Subsequently, postsurgical histopathological examinations were conducted, and she was diagnosed with a plexiform AM pattern. Immunohistochemical staining revealed that the tumor was positive for PCK, P63, CK5/6, and CK14 but negative for S100, ER, and Ki67. Based on these findings, the patient was diagnosed with maxillary AM.

Funder

National Natural Science Foundation of China

The Research Grant of Union Hospital, Tongji Medical College, HUST

Natural Science Foundation of Hubei Province

Publisher

SAGE Publications

Subject

Otorhinolaryngology

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