Laryngeal Involvement in Neurofibromatosis

Abstract

Neurofibromas of the larynx are an uncommon component of neurofibromatosis, but should be considered in the differential diagnosis of patients with a submucosal supraglottic mass. Complete surgical excision is the treatment of choice; however, incomplete excision may be preferable to aggressive debilitatingsurgery. Plexiform neurofibromadiffers from non-plexiform neurofibroma in that it is poorly circumscribed and highly infiltrative. Tracheostomymaybe necessary. Sarcomatous degeneration is reportedandcarries a poor prognosis.