Diffuse-type Tenosynovial Giant Cell Tumor Invading the Temporal Bone: Three Cases

Author:

Huang Qilin1ORCID,Wu Xia1,Xia Qin2,Xie Zhen1,Xiao Hongjun1,Sun Yu1ORCID,Jia Yulin3,Yao Dongxiao4,Guang Xuan5,Cheng Huamao1

Affiliation:

1. Department of Otorhinolaryngology, Huazhong University of Science and Technology, Wuhan, China

2. Department of Pathology, Huazhong University of Science and Technology, Wuhan, China

3. Department of Oral and Maxillofacial Surgery, Huazhong University of Science and Technology, Wuhan, China

4. Department of Neurosurgery, Huazhong University of Science and Technology, Wuhan, China

5. Rollins School of Public Health, Emory University, Atlanta, GA, USA

Abstract

Diffuse-type tenosynovial giant cell tumor (D-TSGCT) is a destructive benign tumor-like proliferative disease that occurs in synovial tissue characterized by villous nodular hyperplasia of joints, tendon sheaths, and synovium. D-TSGCT invading the temporal bone originating from the temporomandibular joint (TMJ) is very rare. Here, we report 3 cases of temporal bone D-TSGCT originating from the TMJ. The tumors in the three cases were originating from the TMJ and further invading the middle ear, the carotid foramen or the temporal lobe respectively. The second patient clearly involved the carotid foramen. The third patient clearly affected the temporal lobe. Lesions were completely removed in 3 cases, and all 3 patients were followed up for 30, 20, and 7 months, and none had recurrence. There are very few reports describing such cases. Although this report is not representative of most scenarios, there is still a potential that it provides a relatively reliable surgical idea for similar cases.

Publisher

SAGE Publications

Subject

Otorhinolaryngology

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