Squamous Cell Carcinoma In Situ Originating From Nasal Polyps With Human Papillomavirus 51 Infection: A Case Report

Author:

Lee Ho Yun1ORCID,Lee Hye Kyung2,Kim Su Jin3

Affiliation:

1. Department of Otorhinolaryngology – Head and Neck Surgery, College of Medicine, Ewha Womans University, Seoul, Republic of Korea

2. Department of Pathology, Eulji University School of Medicine, Daejeon, Republic of Korea

3. Department of Otorhinolaryngology – Head and Neck Surgery, Eulji University School of Medicine, Daejeon, Republic of Korea

Abstract

Malignant transformation of nasal polyps is extremely rare in cases without background inverted papilloma. Human papillomavirus (HPV) is a sexually transmitted infection believed to be associated with oropharyngeal carcinoma via oro-genital sexual contact. We present a case of focal squamous cell carcinoma in situ that occurred on the surface of nasal polyps and was associated with HPV 51. The patient was successfully treated with endoscopic sinus surgery. Clinicians should be aware of the potential for hidden malignancies, and pathologic assessment of tissue specimens must be performed even in simple nasal polyp cases.

Publisher

SAGE Publications

Subject

Otorhinolaryngology

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