Xerostomia and Taste Alterations in COVID-19

Author:

Belchior Fontenele Maria Natally1,Pedrosa Marlus da Silva2ORCID

Affiliation:

1. Course of Dentistry, Centro Universitário UniFacid, PI, Brazil

2. Department of Biomaterials and Oral Biology, Faculdade de Odontologia, Universidade de São Paulo (USP), SP, Brazil

Abstract

A recent letter published in the Ear, Nose & Throat Journal called attention to the hypothesis that the xerostomia reported in patients with the Coronavirus Disease 2019 (COVID-19) occurs due to the neuroinvasive and neurotropism potential of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In fact, angiotensin-converting enzyme 2 (ACE-2), the main site of entry of SARS-CoV-2 into the cell, was found to be present in the ductal elements of salivary gland and several other tissues. However, some points are worth to be addressed.

Publisher

SAGE Publications

Subject

Otorhinolaryngology

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