Sporadic diffuse neurofibroma of the retropharyngeal space

Author:

Colizza Andrea1ORCID,Arienzo Francesca2,Cambria Francesca1,Messineo Daniela3,Riminucci Mara2,Covello Renato4,De Vincentiis Marco1,Corsi Alessandro2ORCID

Affiliation:

1. Department of Sense Organs, Sapienza University of Rome, Roma, Italy

2. Department of Molecular Medicine, Sapienza University of Rome, Roma, Italy

3. Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Roma, Italy

4. Department of Pathology, IRCCS Regina Elena National Cancer Institute, IFO, Rome, Italy

Abstract

Neurofibroma (NF) rarely arises in the retropharyngeal space (RPS) of patients with or without Neurofibromatosis type I (NF-I). The diffuse subtype of NF (DNF) is characterized by an infiltrative growth pattern and typically involves the skin and subcutaneous tissue of the head and neck. We describe the clinic-pathologic features of a DNF involving the RPS of an adult without NF-I. To date, this subtype of NF has never been reported at this site.

Publisher

SAGE Publications

Subject

Otorhinolaryngology

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