High-Grade Sinonasal Small Cell Neuroendocrine Carcinoma in a Patient With Xeroderma Pigmentosum: A Case Report-Reference-Cited by-同舟云学术

High-Grade Sinonasal Small Cell Neuroendocrine Carcinoma in a Patient With Xeroderma Pigmentosum: A Case Report

Published:2024-01-31 Issue: Volume: Page:
ISSN:0145-5613
Container-title:Ear, Nose & Throat Journal
language:en
Short-container-title:Ear Nose Throat J

Author:

Alabdulkareem Abdulaziz M.¹^ORCID,Alotaibi Naif H.¹²,Almobarak Abdulaziz A.¹,Dababo M. Anas³

Affiliation:

1. Department of Otolaryngology-Head & Neck, King Faisal Specialist Hospital and Research Center (KFSH&RC), Riyadh, Saudi Arabia

2. College of Medicine, Alfaisal University, Riyadh, Saudi Arabia

3. Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center (KFSH&RC), Riyadh, Saudi Arabia

Abstract

Neuroendocrine tumors are rare and highly heterogeneous neoplasms with a wide spectrum of histological differentiation, functional, and biological features. Small cell neuroendocrine carcinomas (SNECs) of the sinonasal tract are particularly rare. Pathological features of SNECs of the nasal cavity and paranasal sinuses, which are aggressive tumors, are similar to those of anaplastic small cell carcinomas of the lung. We present a case of high-grade sinonasal SNECs in a patient with Xeroderma pigmentosum complementation group C (XPC) gene-positive xeroderma, which, to our knowledge, is the first case reported worldwide.

Publisher

SAGE Publications

Link

http://journals.sagepub.com/doi/pdf/10.1177/01455613231215198

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