A Large Solitary Fibrous Tumor of the Nasal Cavity and Paranasal Sinuses Involving the Anterior Frontal Fossa: A Case Report and Review of the Literature

Author:

Wu Huachao1ORCID,Hu Xiaoyan1,Xiang Wenbin1,Liu Nuomin1,Fang Sha1,Xu Ting1,Qi Yan1,Zheng Linhui1,Cai Wenqi1,Wu Chaoyan2,Yu Haijun1ORCID

Affiliation:

1. Department of Radiation and Medical Oncology, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University, Wuhan, China

2. Department of Traditional Chinese Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China

Abstract

The Solitary Fibrous Tumor (SFT) is a rare mesenchymal neoplasm that arises mainly from the pleura. The sinonasal tract is generally not affected by SFT, and less than 100 cases have been reported in the English literature to date. We report an extremely rare SFT of the nasal cavity and paranasal sinuses extending into the anterior frontal fossa through the floor of the anterior skull base. To our knowledge, this case is the fourth SFT of the sinonasal tract involving the anterior frontal fossa in the world. Meanwhile, the tumor, measuring 13 × 6 cm in images, is the largest SFT of the sinonasal tract compared to previously reported cases. Three surgical procedures, including a transcranial one, were performed for the patient to achieve complete removal of the tumor. The diagnosis of SFT was established primarily by immunohistochemical positivity for CD34, STAT6, and negativity for S-100 protein. We emphasize the possibility of recurrence in SFT, and close follow-up is necessary with the help of nasal endoscopy and imaging approaches.

Funder

National Natural Science Foundation of China

Publisher

SAGE Publications

Subject

Otorhinolaryngology

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Solitary Fibrous Tumor of Nasal Cavity: A Case Report;Indian Journal of Otolaryngology and Head & Neck Surgery;2024-03-19

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