Follicular Dendritic Cell Sarcoma of the Neck: Case Report and Review of Current Diagnostic and Management Strategies

Author:

Amiri-Kordestani Laleh1,Priebat Dennis2,Chia Stanley H.3

Affiliation:

1. From the Department of Medical Oncology, National Cancer Institute, Bethesda, Md.

2. Department of Hema-tology/Oncology, Washington Hospital Center, Washington, D.C.

3. Department of Otolaryngology, Washington Hospital Center, Washington, D.C.

Abstract

Follicular dendritic cell sarcoma (FDCS) is a rare malignant neoplasm that can clinically mimic a number of other tumors. FDCS can follow either an indolent or aggressive course. The prognosis tends to be worse for patients with large or high-grade tumors and/or an intra-abdominal tumor site. For optimal management, complete surgical excision is recommended. Radiation therapy and/or chemotherapy may be considered for incompletely resected tumors and for tumors with poor prognostic features, but the exact role of adjuvant therapy is unknown. We report a case of cervical FDCS in a 39-year-old black man, and we review the presentation and management of this disorder, with emphasis on the differential diagnosis.

Publisher

SAGE Publications

Subject

Otorhinolaryngology

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