Microsporidium-Associated Sinusitis-Reference-Cited by-同舟云学术

Microsporidium-Associated Sinusitis

Published:1997-02 Issue:2 Volume:76 Page:95-101
ISSN:0145-5613
Container-title:Ear, Nose & Throat Journal
language:en
Short-container-title:Ear Nose Throat J

Author:

Moss Ronald B.¹,Beaudet Lisa M.²,Wenig Bruce M.³,Nelson Ann M.⁴,Firpo Adolfo⁴,Punja Usha²,Scott Thomas S.¹,Kaliner Michael A.¹

Affiliation:

1. Allergic Disease Section, Laboratory of Clinical Investigation, NIAID, NIH, Bethesda, Maryland.

2. Department of Pathology, Washington Hospital Center, Washington, D.C.

3. Department of Otolaryngic-Endocrine Pathology, Armed Forces Institute of Pathology, Washington, D.C.

4. Department of AIDS Registry, Armed Forces Institute of Pathology, Washington, D.C.

Abstract

Two cases of biopsy-proven Microsporidium-associated chronic sinusitis in HIV-seropositive patients are presented. Spores of Septata intestinalis were identified by light microscopy and confirmed by electron microscopy in each case. Both patients displayed severe deficiencies of nasal mucosa CD4-positive cells, demonstrated by immunohistochemical methods. Only two other cases of Septata intestinalis-associated sinusitis have been reported previously. Our observations agree with the theory that functional defects in local mucosal immunity may partially explain the acquisition of opportunistic mucosal infections in many HIV-seropositive patients.

Publisher

SAGE Publications

Subject

Otorhinolaryngology

Link

http://journals.sagepub.com/doi/pdf/10.1177/014556139707600209

Reference19 articles.

1. Microsporidiosis in the Acquired Immunodeficiency Syndrome

2. Microsporidia Infection in Patients with the Human Immunodeficiency Virus and Unexplained Cholangitis

3. Septata Intestinalis N. G., N. Sp., an Intestinal Microsporidian Associated With Chronic Diarrhea and Dissemination In Aids Patients

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