Laryngotracheal Recurrent Papillomatosis: A Case Study and Survey of Surgical and Systemic Management

Author:

Borrelli Michela12ORCID,Nasrollahi Tasha123,Raskin Jonathan124ORCID,Khan Sana5,Alexander Ronda E16

Affiliation:

1. Cedars Sinai Sinus Center of Excellence, Los Angeles, CA, USA

2. Cedars-Sinai Division of Otolaryngology, Los Angeles, CA, USA

3. California Northstate University College of Medicine, Elk Grove, CA, USA

4. Oakland University William Beaumont School of Medicine, Detroit, MI, USA

5. American University of Antigua College of Medicine, Osbourn, AN, USA

6. Montefiore Medical Center, Bronx, NY, USA

Abstract

This case report presents a 72-year-old man with longstanding recurrent respiratory papillomatosis (RRP). He has undergone multiple procedures for the condition, including an apparent urgent surgical airway followed by tracheoplasty repair. Modern management of complicated RRP should include both local debulking and systemic approaches. Systemic bevacizumab (Avastin) has shown some initial success as an effective treatment option, in addition to other medications such as pembrolizumab. Other future care strategies may include an HPV vaccination and other adjuvants; vaccination has been reported to have the possibility of drastically reducing the incidence of RRP.

Publisher

SAGE Publications

Subject

Otorhinolaryngology

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