Response-adaptive designs for continuous treatment responses in phase III clinical trials: A review-Reference-Cited by-同舟云学术

Response-adaptive designs for continuous treatment responses in phase III clinical trials: A review

Published:2012-03-16 Issue:1 Volume:25 Page:81-100
ISSN:0962-2802
Container-title:Statistical Methods in Medical Research
language:en
Short-container-title:Stat Methods Med Res

Author:

Biswas Atanu¹,Bhattacharya Rahul²

Affiliation:

1. Applied Statistics Unit, Indian Statistical Institute, Kolkata, India

2. Department of Statistics, West Bengal State University, Kolkata, India

Abstract

A variety of response-adaptive randomization procedures have been proposed in literature assuming binary outcomes. However, the list is not so long for continuous outcomes though many real clinical trials deal with continuous treatment responses. In this paper, we attempt to explore the available procedures together with a comparison of their performances. Some real-life adaptive trial is also reviewed.

Publisher

SAGE Publications

Subject

Health Information Management,Statistics and Probability,Epidemiology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0962280212441424

Reference82 articles.

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