1. Department of Statistics, University of Warwick, Coventry, UK
2. Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, Zurich, Switzerland
3. SIB Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland
4. Department of Statistical Sciences, University of Padua, Via C. Battisti 241, Padova, Italy