A new risk-adjusted Bernoulli cumulative sum chart for monitoring binary health data

Abstract

To monitor a health event in patients with a specific risk of developing the event, a risk-adjusted cumulative sum chart is needed. The risk-adjusted cumulative sum chart proposed in the literature has some limitations. Setting appropriate control limits is not straightforward, there is no simple formula for constructing them, and they remain sensitive to changes in the underlying risk distribution and the baseline incidence rate. To overcome these limits, we propose a new risk-adjusted Bernoulli cumulative sum chart as a simple and efficient solution. Analyses of simulated and real data sets illustrate the performance and usefulness of the proposed procedure.