Go or Stop? Divergent Roles of Reelin in Radial Neuronal Migration-Reference-Cited by-同舟云学术

Go or Stop? Divergent Roles of Reelin in Radial Neuronal Migration

Published:2010-08 Issue:4 Volume:16 Page:421-434
ISSN:1073-8584
Container-title:The Neuroscientist
language:en
Short-container-title:Neuroscientist

Author:

Zhao Shanting¹,Frotscher Michael²

Affiliation:

1. Institute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany

2. Institute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany,

Abstract

Neuronal migration is an essential step of brain development and is controlled by a variety of cellular proteins and extracellular matrix molecules. Reelin, an extracellular matrix protein, is required for neuronal migration. Over the past 10 years, the Reelin signaling cascade has been studied intensively. However, the role of Reelin in neuronal migration has remained unclear. Different Reelin fragments and different Reelin receptors suggest multiple functions of Reelin. In this review, the authors focus on Reelin effects on the actin cytoskeleton of migrating neurons.

Publisher

SAGE Publications

Subject

Neurology (clinical),General Neuroscience

Link

http://journals.sagepub.com/doi/pdf/10.1177/1073858410367521

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