Experience with the combination of dutasteride and tamsulosin in the long-term management of benign prostatic hyperplasia-Reference-Cited by-同舟云学术

Experience with the combination of dutasteride and tamsulosin in the long-term management of benign prostatic hyperplasia

Published:2012-08-20 Issue:5 Volume:4 Page:267-272
ISSN:1756-2872
Container-title:Therapeutic Advances in Urology
language:en
Short-container-title:Therapeutic Advances in Urology

Author:

Chughtai Bilal¹,Elterman Dean S.¹,Lee Richard¹,Te Alexis E.¹,Kaplan Steven A.²

Affiliation:

1. James Buchanan Brady Department of Urology, Weill Cornell Medical College of Cornell University, New York, USA

2. James Buchanan Brady Department of Urology, Weill Cornell Medical College of Cornell University, 525 East 68th Street, F9West, Box 261, New York, NY 10065, USA

Abstract

Lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) commonly affect older men. These bothersome symptoms can lead to a decreased quality of life. Currently, two classes of drugs – α-adrenergic blockers and 5α-reductase inhibitors – are prescribed to treat LUTS secondary to BPH. Due to their different mechanisms of action, these medications work in a synergistic manner. Trials of combination therapy have been conducted to assess its effect compared with monotherapy. Current data support combination therapy in men with moderately enlarged prostates and moderate to severe symptoms.

Publisher

SAGE Publications

Subject

Urology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1756287212457115

Reference32 articles.

1. Evaluation and Treatment of Lower Urinary Tract Symptoms in Older Men

2. Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability

3. Saw Palmetto for Benign Prostatic Hyperplasia

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