Intralesional collagenase in the treatment of Peyronie’s disease-Reference-Cited by-同舟云学术

Intralesional collagenase in the treatment of Peyronie’s disease

Published:2013-12-23 Issue:2 Volume:6 Page:47-53
ISSN:1756-2872
Container-title:Therapeutic Advances in Urology
language:en
Short-container-title:Therapeutic Advances in Urology

Author:

Honig Stanton C.¹

Affiliation:

1. Department of Urology, Yale University, 330 Orchard St, Suite 164, New Haven, CT 06511, USA

Abstract

The objective of intralesional pharmacotherapy in the treatment of Peyronie’s disease is to deliver large doses of pharmacologic agents that can have a local effect on wound remodeling, with minimal side effects. Guidelines for the treatment of peyronie’s disease published in the Journal of Sexual Medicine and the European Association of Urology offer no grade A evidence of efficacy with multiple agents such as steroids, verapamil and interferon. Intralesional collagenase is the first drug to be approved by the United States Food and Drug Administration for the treatment of Peyronie’s disease. This is based on grade A evidence. The purpose of this update is to review the literature and current data on intralesional collagenase in the treatment of Peyronie’s disease.

Publisher

SAGE Publications

Subject

Urology

Link

http://journals.sagepub.com/doi/pdf/10.1177/1756287213509849

Reference16 articles.

1. Chemonucleolysis (Discolysis) with Collagenase

2. Clinical Efficacy, Safety and Tolerability of Collagenase Clostridium Histolyticum for the Treatment of Peyronie Disease in 2 Large Double-Blind, Randomized, Placebo Controlled Phase 3 Studies

3. The Use of Collagenase in the Treatment of Peyronie’s Disease

4. Phase 2b Study of the Clinical Efficacy and Safety of Collagenase Clostridium Histolyticum in Patients With Peyronie Disease

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