Wilhelm Keller MD (1818–1877) and the emergence of xenobiochemistry-Reference-Cited by-同舟云学术

Wilhelm Keller MD (1818–1877) and the emergence of xenobiochemistry

Published:2024-08-16 Issue: Volume: Page:
ISSN:0967-7720
Container-title:Journal of Medical Biography
language:en
Short-container-title:J Med Biogr

Author:

Mitchell Stephen¹^ORCID,Waring Rosemary²

Affiliation:

1. Faculty of Medicine, Imperial College London, London, UK

2. School of Biosciences, University of Birmingham, Birmingham, UK

Abstract

Although there had been many previous inklings, the field of xenobiotic metabolism (as we know it today) began with an experiment reported in the 1841 literature proclaiming that the ingestion of benzoic acid led to the subsequent excretion of hippuric acid in human urine. A metabolic transformation undertaken by a living organism. One worker involved in the early stages of this discovery was Wilhelm Keller, although very little information about him is readily available. Hopefully, this article will go some way to counter this dearth and also highlight Keller's pioneering contribution in the development of the fields of drug metabolism and xenobiochemistry.

Publisher

SAGE Publications

Link

https://journals.sagepub.com/doi/pdf/10.1177/09677720241273694

Reference47 articles.

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3. On Gouty Concretions, with a New Method of Treatment

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