Revisión: Implicaciones toxicológicas y nutricionales de la toxina T-2 / Review: Toxicological and nutritional implications of T-2 toxin

Author:

Leal M.1,González de Mejía E.2

Affiliation:

1. Facultad de Estudios Superiores Cuautitlán. Universidad Nacional Autónoma de México. Apartado Postal 2-29, Querétaro, Qro. 76020 México

2. Universidad Autónoma de Querétaro. Facultad de Química. Centro Universitario. Cerro de las Campanas. Querétaro, Qro. 76049 México

Abstract

Trichothecenes are mycotoxins produced by species of the genus Fusarium. These toxins are associated with health problems in humans and animals. The most common trichothecenes in cereals are deoxynivalenol, HT-2 toxin, diacetoxyscirpenol, nivalenol, neosolaniol and T-2 toxin; the latter is the most widely studied because it is easy to produce in the laboratory. The effects of T-2 toxicosis include dermatonecrosis, reduced body weight and efficiency of food utilization, severe diarrhoea, haemorrhage, necrosis of the upper alimentary tract, anaemia, immuno suppression ; and in birds, poor feathering. This paper reviews the latest information about the occurrence, chemical characteristics, toxicity, metabolic alterations, biotransformation and detoxifi cation methods of the T-2 toxin.

Publisher

SAGE Publications

Subject

Industrial and Manufacturing Engineering,General Chemical Engineering,Food Science

Reference88 articles.

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3. Pharmacokinetics of the trichothecene mycotoxin, T-2 toxin, in swine and cattle

4. Beremand M.N. y McCormick S. (1992). Biosynthesis and regulation of trichothecene production by Fusarium species. En: Bhatanagar D., Lillehoj E.B. y Arora D.K. (eds), Handbook of Applied Mycology, Mycotoxins in Ecological Systems. Neuva York: Marcel Dekker Inc. pp. 359-384.

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