Effects of a Gastric Feeding Protocol on Efficiency of Enteral Nutrition in Critically Ill Infants and Children

Abstract

Objective: Enteral nutrition (EN) has well-established benefits in critically ill children. Optimally, full nutritional support should be achieved expeditiously. The authors hypothesized that a protocolized continuous gastric EN (GEN) approach would decrease time to goal feeding rate and calories (TTG). Design: 96 patients were enrolled, divided equally into control (pre) and treatment (post) groups. Patients were monitored every 4 hours for 5 signs of feeding intolerance. Significance was defined as P < .05. Setting: 23-bed multidisciplinary pediatric intensive care unit (PICU). Subjects: PICU patients <18 years of age in whom GEN was to be started were eligible. Exclusion criteria included patients receiving total parental nutrition, <24 hours postoperative, had transpyloric feeding, had previous fundoplication, had preexisting gastrointestinal disease or chronic regimen. Interventions: The authors instituted a protocolized, weight-based approach to GEN and collected outcomes and tolerance data on both the control and treatment groups. Measurements and Main Results: There was no difference in TTG between the control and treatment groups. However, for patients less than 10 kg (74/96 patients), TTG was 15 hours faster in the treatment group compared with the control (56.85 ± 22.71, 70.44 ± 32.45 hours, respectively). Conclusions: The authors investigated the value of a GEN protocol in improving efficiency to goal nutrition in critically ill children. While no difference was found overall, in the subgroup analysis (77%) a significant improvement in TTG was found in infants <10 kg. Further investigation is needed to define impact on patient outcomes, such as length of stay, weight gain, and ICU morbidities.