Minimally Invasive Aortic Valve Surgery in Octogenarians: Reliable Option or Fallback Solution?

Author:

Cammertoni Federico1,Bruno Piergiorgio1,Rosenhek Raphael2,Pavone Natalia1,Farina Piero1,Mazza Andrea1,Iafrancesco Mauro1,Nesta Marialisa13,Chiariello Giovanni A.3,Comerci Gianluca1,Pasquini Annalisa1,Cavaliere Franco34,Guarneri Sergio4,Marzetti Emanuele35ORCID,Rabini Alessia6,Piarulli Alessandra7,Sanesi Valerio3,D’Errico Denise8,Massetti Massimo13

Affiliation:

1. Cardiac Surgery Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy

2. Department of Cardiology, Vienna General Hospital, Medical University of Vienna, Austria

3. Catholic University of the Sacred Heart, Rome, Italy

4. Intensive Care Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy

5. Neurosciences and Orthopedics, Fondazione Policlinico Universitario “A.Gemelli” IRCCS, Rome, Italy

6. Physical Medicine and Rehabilitation Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy

7. Clinical Psychology Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy

8. Perfusion Unit, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Rome, Italy

Abstract

Objective Aortic valve disease is more and more common in western countries. While percutaneous approaches should be preferred in older adults, previous reports have shown good outcomes after surgery. Moreover, advantages of minimally invasive approaches may be valuable for octogenarians. We sought to compare outcomes of conventional aortic valve replacement (CAVR) versus minimally invasive aortic valve replacement (MIAVR) in octogenarians. Methods We retrospectively collected data of 75 consecutive octogenarians who underwent primary, elective, isolated aortic valve surgery through conventional approach (41 patients, group CAVR) or partial upper sternotomy (34 patients, group MIAVR). Results Mean age was 81.9 ± 0.9 and 82.3 ± 1.1 years in CAVR and MIAVR patients, respectively ( P = 0.09). MIAVR patients had lower 24-hour chest drain output (353.4 ± 207.1 vs 501.7 ± 229.9 mL, P < 0.01), shorter mechanical ventilation (9.6 ± 2.4 vs 11.3 ± 2.3 hours, P < 0.01), lower need for blood transfusions (35.3% vs 63.4%, P = 0.02), and shorter hospital stay (6.8 ± 1.6 vs 8.3 ± 4.3 days, P < 0.01). Thirty-day mortality was zero in both groups. Survival at 1, 3, and 5 years was 89.9%, 80%, and 47%, respectively, in the CAVR group, and 93.2%, 82.4%, and 61.8% in the MIAVR group, with no statistically significant differences (log-rank test, P = 0.35). Conclusions Aortic valve surgery in older patients provided excellent results, as long as appropriate candidates were selected. MIAVR was associated with shorter mechanical ventilation, reduced blood transfusions, and reduced hospitalization length, without affecting perioperative complications or mid-term survival.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Surgery,Pulmonary and Respiratory Medicine

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. An international survey-based assessment of minimally invasive mitral valve surgery;Interdisciplinary CardioVascular and Thoracic Surgery;2023-09-15

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