Dapsone-Associated Methemoglobinemia in a Patient With SlowNAT2*5B Haplotype and Impaired Cytochromeb5Reductase Activity

Author:

Abouraya Mahmoud,Sacco James C.,Hayes Kristie,Thomas Sajeve,Kitchens Craig S.,Trepanier Lauren A.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference44 articles.

1. Lower risk of urinary tract infection with low-dose trimethoprim/sulfamethoxazole compared with dapsone prophylaxis in older renal transplant patients on a rapid steroid-withdrawal immunosuppression regimen;Giullian;Clin Transplant,2009

2. Acquired methemoglobinemia: a retrospective series of 138 cases at 2 teaching hospitals;Ash-Bernal;Medicine (Baltimore),2004

3. Methemoglobin formation by hydroxylamine metabolites of sulfamethoxazole and dapsone: implications for differences in adverse drugs reactions;Reilly;J Pharmacol Exp Ther,1999

4. Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes;Ganesan;Toxicol Appl Pharmacol,2009

5. CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone;Winter;Drug Metab Dispos,2000

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