Composite Functional Genetic and Comedication CYP2D6 Activity Score in Predicting Tamoxifen Drug Exposure Among Breast Cancer Patients

Author:

Borges Silvana,Desta Zeruesenay,Jin Yan,Faouzi Azzouz,Robarge Jason D.,Philip Santosh,Nguyen Anne,Stearns Vered,Hayes Daniel,Rae James M.,Skaar Todd C.,Flockhart David A.,Li Lang

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference37 articles.

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2. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future;Ingelman-Sundberg;Trends Pharmacol Sci,2004

3. Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6;Desta;J Pharmacol Exp Ther,2004

4. Genetically deficient CYP2D6 metabolism provides protection against oral opiate dependence;Tyndale;Pharmacogenetics,1997

5. Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population;Dahl;Clin Pharmacol Ther,1992

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