Sequential First-Pass Metabolism of Nortilidine: The Active Metabolite of the Synthetic Opioid Drug Tilidine

Author:

Hajda Jacek Piotr,Jähnchen Eberhard,Øie Svein,Trenk Dietmar

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference8 articles.

1. The opiate-like action of tilidine is mediated by metabolites;Schulz;Naunyn-Schmiedeberg's Arch Pharmacol,1978

2. Metabolism of ethyl DL-trans-2-dimethylamino-1-phenylcyclohex-3-ene-trans-1-carboxylate hydrochloride: 1. Mass spectroscopic structural elucidation of metabolites I and II and their determination in various biological fluids;Vollmer;Arzneim-Forsch (Drug Res),1974

3. Human pharmacokinetics of the new potent analgesic DL-trans-2-di-methylamino-1-phenyl-cyclohex-3-en-trans-1-carboxylic acid ethyl ester hydrochloride: 1. Blood level and excretion with urine and feces after single oral administration of 14C-labeled substance;Vollmer;Arzneim-Forsch (DrugRes),1970

4. Pharmacokinetics of tilidine and metabolites in man;Vollmer;Arzneim-Forsch (Drug Res),1989

5. Primary, secondary, and tertiary metabolite kinetics;St-Pierre;J Pharmacokinet Biopharm,1988

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