Pharmacokinetics of Dextromethorphan After Single or Multiple Dosing in Combination With Quinidine in Extensive and Poor Metabolizers

Author:

Pope Laura E.,Khalil M. H.,Berg James E.,Stiles Mark,Yakatan Gerald J.,Sellers Edward M.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference47 articles.

1. Dextromethorphan: enhancing its systemic availability by way of low-dose quinidine-mediated inhibition of cytochrome P4502D6;Zhang;Clin Pharmacol Ther.,1992

2. Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies;Palmer;Curr Drug Targets,2001

3. Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation;Liu;J Pharmacol Exp Ther.,2003

4. Metabolism to dextrorphan is not essential for dextromethorphan's anticonvulsant activity against kainate in mice;Kim;Life Sci.,2003

5. Contribution of cytochrome P-4502D6 phenotype to the neuromodulatory effects of dextromethorphan;Desmeules;J Pharmacol Exp Ther.,1999

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