Pharmacokinetics of a Recombinant Modified Amino Terminal Fragment of Bactericidal/Permeability‐Increasing Protein (rBPI 21 ) in Healthy Volunteers
Author:
Affiliation:
1. XOMA (US)LLC, Berkeley, California
2. Protein Design Labs, Fremont, California
3. Abgenix Corporation, Fremont, California
4. Peninsular Testing Corporation, Miami, Florida
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1177/009127009903901109
Reference18 articles.
1. Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytes;Weiss J;J Biol Chem,1978
2. Expression and Characterization of Cysteine-Modified Variants of an Amino-Terminal Fragment of Bactericidal/Permeability-Increasing Protein
3. High‐affinity binding of the bactericidal/permeability‐increasing protein and a recombinant amino‐terminal fragment to the lipid A region of lipopolysaccharide;Gazzano‐Santoro H;Infect Immun,1992
4. Inhibition of the effects of lipopolysaccharide on endothelial cells by rBPI21, a recombinant fragment of bactericidal/permeability‐increasing protein;Meszaros K;Immune Consequences of Trauma, Shock, and Sepsis: Mechanisms and Therapeutic Approaches,1996
5. Role of the bactericidal/permeability-increasing protein in host defence
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