Effect of Hepatic Impairment on the Pharmacokinetics of Pasireotide (SOM230): Results From a Multicenter Phase I Study

Author:

Horsmans Yves,Hu Ke,Ruffin Matthieu,Wang Ying,Song Dongweon,Bouillaud Emmanuel,Wang Yanfeng,Mazur Dago,Botha Frans-Peter,Heuman Douglas M.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference15 articles.

1. Pasireotide (SOM230): development, mechanism of action and potential applications;Schmid;Mol Cell Endocrinol,2008

2. Pasireotide (SOM230) demonstrates efficacy and safety in patients with acromegaly: a randomized, multicenter, phase II trial;Petersenn;J Clin Endocrinol Metab,2010

3. The effects of pasireotide (SOM230) on health-related quality of life in patients with metastatic carcinoid tumors refractory or resistant to octreotide LAR;Kvols;J Clin Oncol,2007

4. Efficacy, safety and pharmacokinetic results from a Phase II study of pasireotide (SOM230) in the treatment of patients with metastatic NETs refractory or resistant to octreotide LAR;Kvols;Neuroendocrinology,2010

5. Treatment of pituitary dependent Cushing's disease with the multi-receptor ligand somatostatin analog pasireotide (SOM230): A multicenter, phase II trial;Boscaro;J Clin Endocrinol Metab,2009

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