Effect of Rofecoxib on the Pharmacokinetics of Digoxin in Healthy Volunteers

Author:

Schwartz Jules I.,De Smet Marina,Larson Pat J.,Verbesselt R.,Ebel David L.,Lins Robert,Lens Simonne,Porras Arturo G.,Gertz Barry J.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference28 articles.

1. Rofecoxib [Vioxx, MK-0966; 4-(4′-Methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor: pharmacological and biochemical profiles;Chan;J Pharmacol Exp Ther,1999

2. Selective inhibition of the cyclooxygenase-2 isoform: evaluation of analgesic response in patients following third molar extraction;Ehrich;Clin Pharmacol Ther,1999

3. Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans;Depré;Euro J Clin Pharm,2000

4. Selective inhibition of cyclooxygenase type-2 reverses endotoxin-induced fever in monkeys and naturally occurring fever in humans;Schwartz;Clin Pharmacol Ther,1999

5. Human cyclooxygenase-2 cDNA;Hla;Proc Natl Acad Sci USA,1992

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