Methodological Quality of Systematic Reviews and Meta-analyses Published in High-Impact Otolaryngology Journals

Author:

Martinez-Monedero Rodrigo1,Danielian Arman2,Angajala Varun3,Dinalo Jennifer E.4,Kezirian Eric J.1

Affiliation:

1. USC Caruso Department of Otolaryngology–Head & Neck Surgery, Keck School of Medicine of USC, California, USA

2. Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

3. Keck School of Medicine of USC, Los Angeles, California, USA

4. Health Sciences Libraries, Keck School of Medicine of USC, Los Angeles, California, USA

Abstract

Objective To assess the methodological quality of intervention-focused systematic reviews (SRs) and meta-analyses (MAs) published in high-impact otolaryngology journals. Data Sources Ovid Medline, Embase, and Cochrane Library. Review Methods A comprehensive search was performed for SR and MA citations from 2012 to 2017 in the 10 highest impact factor otolaryngology journals. Abstracts were screened to identify published manuscripts in which the authors indicated clearly that they were performing an SR or MA. Applying a modified typology of reviews, 4 reviewers characterized the review type as SR, MA, or another review type. A simplified version of the AMSTAR 2 (A MeaSurement Tool to Assess systematic Reviews 2) tool was used to assess the reporting and methodological quality of the SRs and MAs that were focused on interventions. Results Search and abstract screening generated 499 manuscripts that identified themselves as performing an SR or MA. A substantial number (85/499, 17%) were review types other than SRs or MAs, including 34 (7%) that were literature reviews. In total, 236 SRs and MAs focused on interventions. Over 50% of these SRs and MAs had weaknesses in at least 3 of the 16 items in the AMSTAR 2, and over 40% had weaknesses in at least 2 of the 7 critical domains. Ninety-nine percent of SRs and MAs provided critically low confidence in the results of the reviews. Conclusion Intervention-focused SRs and MAs published in high-impact otolaryngology journals have important methodological limitations that diminish confidence in the results of these reviews.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

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