Effect of Ibuprofen Upon Hearing in the Guinea Pig

Author:

Koopmann Charles F.1,Glattke Theodore A.2,Caffrey Jill D.2

Affiliation:

1. From the Section of Otolaryngology, Department of Surgery, University of Arizona Health Sciences Center, University of Arizona, Tucson

2. Department of Speech and Hearing, University of Arizona, Tucson

Abstract

The authors investigated the effect of varying doses of ibuprofen upon the hearing of guinea pigs monitored with brain stem-evoked response procedures. In daily dosages comparable on a weight basis to therapeutic levels in humans, ibuprofen was found not to have significant effects on response threshold or latency characteristics.

Publisher

SAGE Publications

Subject

Otorhinolaryngology,Surgery

Reference9 articles.

1. Evaluation of Ibuprofen (Motrin)

2. Stubbs SS, Stubbs DF, Bremer WM, Clinical Brochure for Investigators Studying Ibuprofen and Myocardial Infarction. Kalamazoo, Mich, The Upjohn Company, 1978, pp 1–38.

3. Recent Advances in Otologic Radiology

4. Aspirin Ototoxicity in the Guinea Pig

5. Salicylate Ototoxicity: A Clinical and Experimental Study

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